Leprosy reactions.

sulfatide antibodies in leprosy and leprosy reactions

Vasculonecrotic reactions in leprosy.

Multibacillary, lepromatous or borderline leprosy patients may present two types of vasculonecrotic reactions: Lucio phenomenon and that associated with erythema nodosum leprosum. Despite they can be distinguished through clinical and histological characteristics; both are often used as synonyms. It is said that leprosy reaction should be properly classified for therapeutic reasons, since it is...

Chloroquine for Reactions in Leprosy.

.An. interesting observation was made in a large leprosy colony in Nigeria in 1958. Five hundred patients were kept on pyrimethamine prophylaxis for malaria for one year, and during this period the incidence of lepra reaction among these cases was found to be reduced [Bruce-Chwatt and Horn (l)]. This observation raised the possibility that antimalarials might be effective in the treatment of re...

Lymphocyte transfer reactions in leprosy patients.

We have demonstrated that allograft immunity is impaired in leprosy patients, especially patients with lepromatous leprosy ( 4). This finding indicates that the lymphocytes of leprosy patients are immunologically defective with respect to their activities in vivo, a concept which is supported by the in vitro work of others on lymphocyte transformation (2, 3, 8), and our recent work on lymphotox...

Ocular changes in reactions in leprosy.

A study of ocular changes in reactions in leprosy was undertaken to assign these changes, their proper place in the wide spectrum of ocular morbidity in leprosy. 76.1% of eyes of Type I reaction and 89.7% of eyes with Type II reaction showed some ocular involvement. Corneal hypoaesthesia, superficial punctate keratitis, a decrease of corneal film break up time (BUT), prominent corneal nerves, p...